| Pos | Team | Pld | Pts | GD | W | D | L | F | A |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Southampton | 42 | 61 | +47 | 23 | 15 | 4 | 68 | 21 |
| 2 | Plymouth Argyle | 42 | 61 | +39 | 25 | 11 | 6 | 63 | 24 |
| 3 | Portsmouth | 42 | 53 | +23 | 18 | 17 | 7 | 62 | 39 |
| 4 | Luton Town | 42 | 52 | +29 | 22 | 8 | 12 | 64 | 35 |
| 5 | Queens Park Rangers | 42 | 49 | +9 | 18 | 13 | 11 | 53 | 44 |
| 6 | Swindon Town | 42 | 45 | +12 | 16 | 13 | 13 | 72 | 60 |
| 7 | Watford | 42 | 44 | +6 | 13 | 18 | 11 | 54 | 48 |
| 8 | 42 | 44 | +6 | 17 | 10 | 15 | 57 | 51 | |
| 9 | Brentford | 42 | 43 | +9 | 16 | 11 | 15 | 52 | 43 |
| 10 | Swansea Town | 42 | 41 | +3 | 13 | 15 | 14 | 50 | 47 |
| 11 | 42 | 40 | -11 | 17 | 6 | 19 | 45 | 56 | |
| 12 | Millwall | 42 | 38 | -4 | 10 | 18 | 14 | 38 | 42 |
| 13 | Reading | 42 | 38 | -7 | 14 | 10 | 18 | 40 | 47 |
| 14 | Bristol Rovers | 42 | 38 | -15 | 14 | 10 | 18 | 52 | 67 |
| 15 | Norwich City | 42 | 37 | -12 | 12 | 13 | 17 | 50 | 62 |
| 16 | Charlton Athletic | 42 | 37 | -13 | 13 | 11 | 18 | 43 | 56 |
| 17 | Northampton Town | 42 | 37 | -24 | 13 | 11 | 18 | 47 | 71 |
| 18 | Gillingham | 42 | 36 | -13 | 14 | 8 | 20 | 47 | 60 |
| 19 | Brighton & Hove Albion | 42 | 35 | -6 | 13 | 9 | 20 | 45 | 51 |
| 20 | Newport County | 42 | 34 | -17 | 11 | 12 | 19 | 44 | 61 |
| 21 | Exeter City | 42 | 34 | -21 | 11 | 12 | 19 | 38 | 59 |
| 22 | Southend United | 42 | 27 | -40 | 8 | 11 | 23 | 34 | 74 |
Content retrieved from: http://stats.football.co.uk/league_tables/1921_1922/third_division_south/index.shtml.
