Covid 19-other vaccines may help

[Professor]

Interesting new study published today
https://www.cell.com/cell/fulltext/S0092-8674(20)31139-9

In simple terms there is a phenomenon called trained immunity which means some vaccines 'prime' cells called macrophages to protect in a non-specific way for about 6 months. This is not a specific antibody or cell response to the vaccines, but more like putting these early responders on 'red alert". Here they use the old TB vaccine BCG (which is not that effective any more) in over 65s to boost the immune system in the respiratory tract-its also a response where excessive inflammation is controlled. Early days but hopefully seasonal flu vaccines may help (some flu vaccines have been shown to produce this effect in mice). What is good is that is in older people, where the immune system often struggles.

 

[Scotia]

Potentially excellent news. Is this associated with the Austrailian research?

 

[Cooperman]

I don't recall seeing or hearing of a recent update concerning the Oxford project. Anyone paying close attention to it and if so what is the consensus?

 

[Scotia]

I don't recall seeing or hearing of a recent update concerning the Oxford project. Anyone paying close attention to it and if so what is the consensus?

I think it is in phase 3 trials in Brazil and S. Africa with results due around the end of 2020?

 

[Professor]

I don't recall seeing or hearing of a recent update concerning the Oxford project. Anyone paying close attention to it and if so what is the consensus?

I think it is in phase 3 trials in Brazil and S. Africa with results due around the end of 2020?

Yes, that is correct. Also where a few of the Oxford/Jenner vaccines have failed.
However, since Astra Zeneca are moving forward on the vaccine, it may be good news.

 

[Professor]

Potentially excellent news. Is this associated with the Austrailian research?

No. US-based. The idea has been around about 10 years, but no one has shown any effect in the elderly (immunosenescent) population before

 

[A4Jack]

With the increasingly low death rates despite so called high infection rates this may be the sort of antidote to really bring things back to normal.

But it won't and we won't be