Its time...

[Professor]

Just one or two like TB, Bordetella, influenza,
Smallpox, diphtheria, mumps, typhoid, yellow fever, hepatitis B, A and C. Haemophilus, meningococcal meningitis, Pneumococcus, rotavirus, tetanus. Plus hundreds of veterinary vaccines including coronaviruses. It is not a hugely variable virus. We tend to fail when there is huge variability or complex life cycles. There are always exceptions like HIV, but generally we get vaccines for viruses if the investment is there. And don’t say colds as they are caused by multiple variants of multiple virus families.

Ok you have no doubt googled the amount of vaccines they have found, now go and Google the vaccines they have not been able to find for various illness and decease, and guess what it it more than trebles that list you have posted, as i say there is certainly no guarantee that they will be able to find a vaccine or cure for a long time if at all.

I did not google it. I teach this to vets and biologists. Also worked on efficacy trials of some of these 25 years ago

The big diseases - which have big mortality without vaccines include malaria, HIV, Leishmaniasis, Trypanosomiasis and Salmonella (though there are Veterinary vaccines).
Most (HIV being a notable exception) have large antigen variation and complex multi-stage life cycles. SARS CoV2 does not. Has a really nice vaccine target too- called the spike protein.

 

[Jack12345]

So Mr Professor you do agree then that there are plenty of diseases out there where vaccines have not been found and my point is simply when someone states a vaccine will be found for Covid, they are simply speculating, hopefully they will find one, but it is quite possible they will not, or maybe we may have to wait years until they do, who knows.

 

[Neath_Jack]

One local field hospital being doubled in size, got to be finished within a month.

New isolation ward being constructed in the Royal Glamorgan hospital as we speak.

Hospital admissions starting to fly up now.

 

[Professor]

So Mr Professor you do agree then that there are plenty of diseases out there where vaccines have not been found and my point is simply when someone states a vaccine will be found for Covid, they are simply speculating, hopefully they will find one, but it is quite possible they will not, or maybe we may have to wait years until they do, who knows.

No. There are vaccines for other coronaviruses just in chickens and pigs. Both similar to Covid in terms of disease. SARS and MERS were not widespread enough for huge investment . As I will say for the third time with the exception of HIV, although it’s nature of attacking Th cells does not help vaccines, major diseases without vaccines tend to be parasites with complex life cycles and more variation.

 

[Jack2jack]

Let's say that a vaccine is miles away from being ready, worst case scenario,never, then we may have to live side by side with it.What do we do then,we would have to get the economy back on track and get back to some sort of normality. I know this may not sit we'll with folk,however, this maybe the reality,should a vaccine not be found.How far away is this vaccine anyway, 1 year, 2 years, 5 years what's it to be. In which case we would have to live with it
How long do these restrictions and lockdowns last, I hear everyday, 'until we find the vaccine', great, but its if, not when.This virus sure as hell ain't going away any time soon. This is my frustration with the current situation.
So unless Boris the clown and his cohort's know different, and the silver bullet is waiting in the wings, we may as I've said have to live with this for a long time,maybe forever.
I know some are going to jump all over this opinion,and it's just that, it maybe the reality,only time will tell.

I took the view back in mid July that I was going to take what I saw as the common sense approach whilst at the same time attempting a normal day to day routine. My work commute is to one of the last few places that you can get to in mainland Europe without the need for quarantine so most weeks I have flown out on a Monday and back on a Thursday or Friday. There is a rigorous workplace regime in place for social distancing and health & safety and the hotel is also very well organised. When I'm home I largely distance myself from family members who are at greater risk than the household and this is no real impact as I would not have got close to elderly parents and in-laws even if I had remained at home. This coupled with the COVID stats meant that it became a fairly easy choice about how to define a new normal lifestyle. Similarly to above, this is also quite possibly an unpopular stance.

Sounds sensible to me Coops, and pretty much, how we have carried on with life, the missus is now back in work after a lengthy stretch on furlough, I have also gone back into work, after finding home working difficult, no problems so far, so long as you follow the rules. My main point above of course is, that if a vaccine isn't found, then it is possible to live along side this virus, albeit, things maybe a little limited in terms of what can and can't be done. I would say that large enclosed gatherings may not be possible for a long while yet.
I really fear that the economy is starting to creak, and once the government runs out of all this money, they have found down the back of the sofa, times are going to get really quite tough.
Let's hope that a vaccine can be found, but in the meantime we may just have to live with this virus, obviously shielding the vulnerable, and kick-starting the economy in equal measure. Tough times ahead for everyone.

 

[Professor]

I took the view back in mid July that I was going to take what I saw as the common sense approach whilst at the same time attempting a normal day to day routine. My work commute is to one of the last few places that you can get to in mainland Europe without the need for quarantine so most weeks I have flown out on a Monday and back on a Thursday or Friday. There is a rigorous workplace regime in place for social distancing and health & safety and the hotel is also very well organised. When I'm home I largely distance myself from family members who are at greater risk than the household and this is no real impact as I would not have got close to elderly parents and in-laws even if I had remained at home. This coupled with the COVID stats meant that it became a fairly easy choice about how to define a new normal lifestyle. Similarly to above, this is also quite possibly an unpopular stance.

Sounds sensible to me Coops, and pretty much, how we have carried on with life, the missus is now back in work after a lengthy stretch on furlough, I have also gone back into work, after finding home working difficult, no problems so far, so long as you follow the rules. My main point above of course is, that if a vaccine isn't found, then it is possible to live along side this virus, albeit, things maybe a little limited in terms of what can and can't be done. I would say that large enclosed gatherings may not be possible for a long while yet.
I really fear that the economy is starting to creak, and once the government runs out of all this money, they have found down the back of the sofa, times are going to get really quite tough.
Let's hope that a vaccine can be found, but in the meantime we may just have to live with this virus, obviously shielding the vulnerable, and kick-starting the economy in equal measure. Tough times ahead for everyone.

Even with a vaccine it will take some time to return to 'normal', though what is normal may never be quite the same. Part of living with the virus will be restrictions from time to time. I will admit to finding it very hard. Not been in work since March 13th, other than three very brief trips to pick things up I need. Unlikely to be back before March. Researchers working in two bubbles of 2 or 3 days per week. Large tracts of things important still inaccessible. That said, I still as most scientists do that the two week circuit breaker is needed, or this winter is going to be very messy and long. Quicker action would mean less long-term pain.

 

[Jack2jack]

Sounds sensible to me Coops, and pretty much, how we have carried on with life, the missus is now back in work after a lengthy stretch on furlough, I have also gone back into work, after finding home working difficult, no problems so far, so long as you follow the rules. My main point above of course is, that if a vaccine isn't found, then it is possible to live along side this virus, albeit, things maybe a little limited in terms of what can and can't be done. I would say that large enclosed gatherings may not be possible for a long while yet.
I really fear that the economy is starting to creak, and once the government runs out of all this money, they have found down the back of the sofa, times are going to get really quite tough.
Let's hope that a vaccine can be found, but in the meantime we may just have to live with this virus, obviously shielding the vulnerable, and kick-starting the economy in equal measure. Tough times ahead for everyone.

Even with a vaccine it will take some time to return to 'normal', though what is normal may never be quite the same. Part of living with the virus will be restrictions from time to time. I will admit to finding it very hard. Not been in work since March 13th, other than three very brief trips to pick things up I need. Unlikely to be back before March. Researchers working in two bubbles of 2 or 3 days per week. Large tracts of things important still inaccessible. That said, I still as most scientists do that the two week circuit breaker is needed, or this winter is going to be very messy and long. Quicker action would mean less long-term pain.

1800 people died on Britains roads last year, some 25500 were seriously injured, do we ban cars, no we live with the risk, and before anyone starts, if your hit by a lorry and die, there aint no cure. We may have to live with this forever. Lets plan for it now.

 

[Professor]

Even with a vaccine it will take some time to return to 'normal', though what is normal may never be quite the same. Part of living with the virus will be restrictions from time to time. I will admit to finding it very hard. Not been in work since March 13th, other than three very brief trips to pick things up I need. Unlikely to be back before March. Researchers working in two bubbles of 2 or 3 days per week. Large tracts of things important still inaccessible. That said, I still as most scientists do that the two week circuit breaker is needed, or this winter is going to be very messy and long. Quicker action would mean less long-term pain.

1800 people died on Britains roads last year, some 25500 were seriously injured, do we ban cars, no we live with the risk, and before anyone starts, if your hit by a lorry and die, there aint no cure. We may have to live with this forever. Lets plan for it now.

That may be so, but that does not mean a circuit breaker is not what is needed. At current seven days averages you are look at 9,000 deaths and 62,000 hospitalisation to the end of this year. That is without a rise when cases are doubling at 14 days. Without action now we could be looking at another 20,000 deaths this winter (being conservative) and many more with long-term illness. A re-set allows time to plan, though I have seen no evidence that the clown and his puppeteer have one.

 

[Jack2jack]

1800 people died on Britains roads last year, some 25500 were seriously injured, do we ban cars, no we live with the risk, and before anyone starts, if your hit by a lorry and die, there aint no cure. We may have to live with this forever. Lets plan for it now.

That may be so, but that does not mean a circuit breaker is not what is needed. At current seven days averages you are look at 9,000 deaths and 62,000 hospitalisation to the end of this year. That is without a rise when cases are doubling at 14 days. Without action now we could be looking at another 20,000 deaths this winter (being conservative) and many more with long-term illness. A re-set allows time to plan, though I have seen no evidence that the clown and his puppeteer have one.

So time is of the essence, yes, so any restrictions announced on Monday will kick in on Friday...…..does the Virus go on holiday for a few days while we all prepare for lockdown, just asking like.
The whole things a mess. If only we had people in charge that knew what day it was.
Sorry Prof, i'm done, have a great weekend.

 

[sainthelens]

They've had 6 months to get an effective test/track n trace system in place. Widely recognised as the most efficient way of combatting this. Millions have been spent by private companies fckn that up. Boris must be held accountable for that mess. The long game with what they are doing will see riots like the 80s, when nobody has a job crime figures will rocket. What's happening to our elderly is awful, but our youngest will literally have no quality of life the way this is being handled.

 

[Professor]

That may be so, but that does not mean a circuit breaker is not what is needed. At current seven days averages you are look at 9,000 deaths and 62,000 hospitalisation to the end of this year. That is without a rise when cases are doubling at 14 days. Without action now we could be looking at another 20,000 deaths this winter (being conservative) and many more with long-term illness. A re-set allows time to plan, though I have seen no evidence that the clown and his puppeteer have one.

So time is of the essence, yes, so any restrictions announced on Monday will kick in on Friday...…..does the Virus go on holiday for a few days while we all prepare for lockdown, just asking like.
The whole things a mess. If only we had people in charge that knew what day it was.
Sorry Prof, i'm done, have a great weekend.

Yes- and that is another stupid thing-restrictions should be announced and kick in that day, not giving time for people to behave like idiots.
And you have a good one too.

 

[Professor]

They've had 6 months to get an effective test/track n trace system in place. Widely recognised as the most efficient way of combatting this. Millions have been spent by private companies fckn that up. Boris must be held accountable for that mess. The long game with what they are doing will see riots like the 80s, when nobody has a job crime figures will rocket. What's happening to our elderly is awful, but our youngest will literally have no quality of life the way this is being handled.

Amen to that. Should have been PHE/PHW oversight with planning given to local directors of public health. Like Germany, universities could have handled extra diagnostics. The private groups used academics to set up, and problems have increased since they went back to the day job.

Used as an exercise in profiteering. Johnson should be up in court for manslaughter by negligence in my opinion.

 

[BLAZE]

Scheduling lockdowns a few days in advance makes sense to me. If they popped up on the news and announced a lockdown to start with immediate effect there'd be chaos. They'd be accused of making knee jerk reactions and not giving people time to prepare. There'd be carnage in the supermarkets etc. Scheduling is a more measured approach, which is what every decision should be ideally

 

[Cooperman]

Scheduling lockdowns a few days in advance makes sense to me. If they popped up on the news and announced a lockdown to start with immediate effect there'd be chaos. They'd be accused of making knee jerk reactions and not giving people time to prepare. There'd be carnage in the supermarkets etc. Scheduling is a more measured approach, which is what every decision should be ideally

It allows the youth of today to go out on one last bender.

 

[Professor]

Scheduling lockdowns a few days in advance makes sense to me. If they popped up on the news and announced a lockdown to start with immediate effect there'd be chaos. They'd be accused of making knee jerk reactions and not giving people time to prepare. There'd be carnage in the supermarkets etc. Scheduling is a more measured approach, which is what every decision should be ideally

It allows the youth of today to go out on one last bender.

Which was my point.