Best_loser said:
It should affect people, the monkey virus they use in the Oxford vaccine to transport the vaccine produces antibodies, that why people feel a bit rough
Nearly- the vector which carries the spike protein of SARS CoV2 (chimpanzee adenovirus) is essentially a mild infection. The immune system has non-specific receptors (like Toll and NOD receptors) which recognise patterns on pathogens. These set off a ‘danger signal’ and innate immune response which itself causes symptoms like fever and aches. This in turn leads to activation of adaptive immunity that gives rise to antibody, cytotoxic T cells and hopefully memory T and B cells. I got a headache and aching knees.